Title/degree | Doctor, assoc. prof. |
Position | Leading scientific researcher |
Laboratory | Chemistry of Natural and Biologically Active Compounds |
Office | 304 |
Phone/fax | (+373 22) 73 97 69 |
[email protected] [email protected] |
|
Professional links |
Google scholar |
Research areas
- Bioorganic chemistry. Chemistry of natural and biologically active compounds.
- Isolation of secondary metabolitesfrom native plants and vegetal by-products using various techniques.
- Synthesisof new polyfunctionalizedterpenic derivatives or of natural products analogs using conventional and non-conventional methods.
- Structure elucidationby modern analytical methods.
Relevant publications
Projects
Articles in international journals (Web of Science and SCOPUS)
- CIOCARLAN, A., DRAGALIN, I., ARICU, A., LUPASCU, L., CIOCARLAN, N., VERGEL, K., DULIU, O.G., HRISTOZOVA, G., ZINICOVSCAIA, I. Chemical profile, elemental composition, and antimicrobial activity of plants of the Teucrium (Lamiaceae) genus growing in Moldova. In: Agronomy, 2022, 12(4), 772-788. DOI: https://doi.org/10.3390/agronomy12040772 (FI 2.24)
- CIOCARLAN, A., LUPASCU, L., ARICU, A., DRAGALIN, I., POPESCU, V., GEANA, E.I., IONETE, R.E., VORNICU, N., DULIU, O.G., HRISTOZOVA, G., ZINICOVSCAIA, I. Chemical composition and assessment of antimicrobial activity of lavender essential oil and some by-products. In: Plants, 2021, 10(9), 1829-1843. DOI: https://doi.org/10,3390/plants1091829 (FI 3.935). IBN: https://ibn.idsi.md/ro/vizualizare_articol/138166
- URECHE, D., BULHAC, I., CIOCARLAN, A., ROSHCA, D., LUPASCU, L., BOUROSH, P. Novel vic-Dioximes: synthesis, structure characterization and antimicrobial activity evaluation. In: Turkish Journal of Chemistry, 2021, 45(6), 1873-1881. DOI: 10.3906/kim-2104-24 (IF 1.239). IBN: https://ibn.idsi.md/ro/vizualizare_articol/148592
- CIOCARLAN, A., HRISTOZOVA, G., ARICU, A., DRAGALIN, I., ZINICOVSCAIA, I., YUSHIN, N., GROZDOV D., POPESCU, V. Determination of the elemental composition of aromatic plants cultivated industrially in the Republic of Moldova using neutron activation analysis. In: Agronomy, 2021, 11(5), 1011-1030. DOI: 10.3390/agronomy11051011 (IF 2.603). IBN: https://ibn.idsi.md/ro/vizualizare_articol/132488
- GEANĂ, E.-I., CIUCURE, C.T., IONETE, R.E., CIOCARLAN, A., ARICU, A., FICAI, A., ANDRONESCU, E. Profiling of phenolic compounds and triterpene acids in different apple (Malus domestica Borkh.) cultivars. In: Foods, 2021, 10(2), 267-282. DOI: https://doi.org/10.3390/foods10020267 (FI 4.350). IBN: https://ibn.idsi.md/ro/vizualizare_articol/126448
- BLAJA, S.P., LUNGU, L.V., KUCHKOVA, K.I., CIOCARLAN, A.G., BARBA, A.N., VORNICU, N., ARICU, A.N. Norlabdane compounds containing thiosemicarbazone or 1,3-thiazole fragments: Synthesis and antimicrobial activity. In: Chemistry of Natural Compounds, 2021, 57(1), 101-110. DOI: https://doi.org/10.1007/s10600-021-03292-3 (FI 0.809). IBN: https://ibn.idsi.md/ro/vizualizare_articol/126852
- CIOCARLAN, A., LUPASCU, L., ARICU, A., DRAGALIN, I., CIOCARLAN, N., ZINICOVSCAIA, I., SLANINA, V., YUSHIN, N. Chemical composition of the essential oil and antimicrobial properties of crude extract from Tanacetum corymbosum (L.). In: Chemistry Journal of Moldova, 2021, 16(2), 83-90. DOI: 10.19261/cjm.2021.877. IBN: https://ibn.idsi.md/ro/vizualizare_articol/146807
- CIOCARLAN, A. (+)-Larixol and larixyl acetate: syntheses, phytochemical studies and biological activity assessments. In: Chemistry Journal of Moldova. 2021, 16, (1), pp. 30-45. DOI: https://doi.org/10.19261/cjm.2021.836. IBN: https://ibn.idsi.md/ro/vizualizare_articol/134251
- LUNGU, L., CIOCARLAN, A., SMIGON, C., OZER, I., SHOVA, S., GUTU, I., VORNICU, N., MANGALAGIU, I., D'AMBROSIO, M., ARICU, A.. Synthesis and evaluation of biological activity of homodrimane sesquiterpenoids bearing 1,3,4-oxadiazole or 1,3,4-thiadiazole units. In: Chemistry of Heterocyclic Compounds, 2020, 56(5), 578-585. DOI: 10.1007/s10593-019-02526-1. (IF 1.492). IBN: https://ibn.idsi.md/ro/vizualizare_articol/107236
- ZINICOVSCAIA, I., GUNDORINA, S., VERGEL, K., GROZDOV, D., CIOCARLAN, A., ARICU, A., DRAGALIN, I., CIOCARLAN, N. Elemental analysis of Lamiaceae medicinal and aromatic plants growing in the Republic of Moldova using neutron activation analysis. In: Phytochemistry Letters, 2020, 35, 119-127. DOI: 10.1016/j.phytol.2019.10.009 (IF 1.338)
- CIOCARLAN, A., LUNGU, L., BLAJA, S., DRAGALIN, I., ARICU, A. The use of some non-conventional methods in chemistry of bicyclohomofarnesenic methyl esters. In: Chemistry Journal of Moldova, 2020, 15(2), 69-77. DOI: https://doi.org/10.19261/cjm.2020.791. IBN: https://ibn.idsi.md/ro/vizualizare_articol/118145
Articles in abstract books
- ARÎCU, A., LUNGU, L., BLAJA, S., CUCICOVA, C., CIOCÂRLAN, A. Sinteza și studiul activității antimicrobiene a compușilor norlabdanici cu unități structurale heterociclice. In: Acad. A. Gulea - Conferinţa Ştiinţifică Naţională cu participare Internaţională: „Materiale Avansate în Biofarmaceutică şi Tehnică”, Culegere de articole, Chişnău, 2021, p. 10-34.
- ARICU, A., CIOCARLAN A. Synthesis of biologically active terpenoids by valorisation of some vegetable wastes. IN: Conference "Ecological and environmental chemistry 2022" 7th Edition, Chisinau, Moldova, 3-4 March 2022. In: Ecological and environmental chemistry, Vol. 1, p. 146-147, 2022. IBN: https://ibn.idsi.md/ro/vizualizare_articol/151942
Abstracts
- CIOCARLAN, A., BLAJA, S., CUCICOVA, C., LUNGU, L., ARICU, A. Synthesis of some new homodrimane sesquiterpenoids with benzothiazole fragment. In: The 21st Tetrahedron Symposium – Online, 21 – 24 June 2021. (Reg. numb. ETR2021_0478). https://app.oxfordabstracts.com/events/1644/secure/program-app/submission/241532
- LUNGU, L., BLAJA, S., CIOCARLAN, A., DRAGALIN, I., ARICU, A. The electrochemical transformations of methyl bicyclohomofarnesoates. In: New frontiers in natural product chemistry. Online scientific seminar, Chisinau, June 4, 2021, Book of Abstracts, p. 15. DOI: https://doi.org/10.19261/nfnpc.2021.ab08. IBN: https://ibn.idsi.md/ro/vizualizare_articol/131092
- CIOCÂRLAN, A., CAZACU, V., LUNGU, L., BLAJA, S., DRAGALIN, I., ARÎCU, A. The use of non-conventional methods for the isolation of chromatographically inseparable compounds. In: New frontiers in natural product chemistry. Online scientific seminar, Chisinau, June 4, 2021, Book of Abstracts, p. 19. DOI: https://doi.org/10.19261/nfnpc.2021.ab12. IBN: https://ibn.idsi.md/ro/vizualizare_articol/131096
- POPESCU, V., CIOCARLAN, A., DRAGALIN, I., LUNGU, L., ARÎCU, A. Chemical composition of essential oil of Dill (Anethum graveolens L.) growing in Republic of Moldova. In: New frontiers in natural product chemistry. Online scientific seminar, Chisinau, June 4, 2021, Book of Abstracts, p. 35. DOI: https://doi.org/10.19261/nfnpc.2021.ab28. IBN: https://ibn.idsi.md/ro/vizualizare_articol/13114.
- CIOCARLAN, A. Valorisation of some terpenes from vegetable wastes. International Conference “Intelligent Valorisation of Agro-Industrial Wastes”, 07-08 October 2021, Chisinau, Republic of Moldova. IBN: https://ibn.idsi.md/ro/vizualizare_articol/140156
Patents
- ARÎCU, A., CIOCÂRLAN, A., LUNGU, L., BLAJA, S., VORNICU, N. 5-(Homodrim-6,8-dien-11-il)-1,3,4-tiadiazol-2(3H)-imină cu proprietăţi antifungice. Patent MD 4765.
- ARÎCU, A., CIOCÂRLAN, A., LUNGU, L., BLAJA, S., VORNICU, N. (Z/E)-2-(1-((1R,2R,8aS)-2-hidroxi-2,5,5,8a-tetrametildecahidronaftalen-1-il)propan-2-iliden)hidra- zincarbotioamidă pentru utilizare în calitate de remediu antifungic. Patent MD 4769.
- ARÎCU, A., CIOCÂRLAN, A., LUNGU, L., BLAJA, S., VORNICU, N. 5-(Homodrim-6,8-dien-11-il)-1,3,4-tiadiazol-2(3H)-imină cu proprietăţi antifungice. Salonul internațional de invenții și inovații „TRAIAN VUIA” ediția a VII-a, 06-08 octombrie 2021, Timișoara. Gold Medal.
- ARÎCU, A., LUNGU, L., CIOCÂRLAN, A., BLAJA, S., VORNICU, N. Compușii terpenici noi cu fragment tiadiazolic/tiosemicarbazonic cu proprietăți antifungice. EIS „INFOINVENT”, ediția a XVII-a, 17-20 noiembrie 2021, Chișinău. Gold Medal.
National projects
- ANCD/20.80009.8007.03. New products with preventive and therapeutic potential basing on natural products of vegetal origin and modern methods of organic synthesis
Period: 2020-2023
Project manager: Dr. habilitate Veaceslav KULCIȚKI - CSSDT/15.817.02.14A. Elaboration of methods for obtaining valuable terpenoids by valorization of renewable resources from Republic of Moldova
Period: 2015-2019
Project manager: Dr. habilitate, assoc. prof. Nicon UNGUR - CSȘDT/16.00353.50.04A. Design, directed synthesis and study of antibacterial and antitumor activity of chiral terpenic compounds and their coordinative combinations with transition metals
Period: 2016-2017
Project manager: Dr. habilitate, assoc. prof. Aculina ARICU
Internațional projects
- AȘM-STCU/18.80013.5007.01/6330STCU. Synthesis of biologically active norlabdanic compounds with heterocyclic structural units based on agricultural waste.
Period: 2018-2019;
Project manager: Dr. habilitate, assoc. prof. Aculina ARICU