Research Infrastructure Subprojects Financed by the World Bank
Energy, Exact and Natural Sciences: Chemistry
Institute of Chemistry
- Laboratory Chemistry of Natural and Biological Active Compounds
- Laboratory of Organic Synthesis
The specific objectives of the subproject focus on the acquisition of two strategically important analytical modules: a Nuclear Magnetic Resonance (NMR) spectrometer and an Ultra-Performance Liquid Chromatography system coupled with a High-Resolution Mass Spectrometer (UPLC-HRMS). Both modules represent unique research facilities for academic institutions as well as private companies in the Republic of Moldova.
For research purposes, NMR spectroscopy and high-resolution mass spectrometry are indispensable techniques for the structural characterization of individual compounds during isolation and synthesis studies, as well as for publishing research findings in high-impact international scientific journals. In this context, both modules are essential for all disciplines related to the molecular sciences. The coupling of a high-resolution mass spectrometer with a UPLC system enables advanced investigations of biologically active natural compounds, facilitating their identification and quantification in local plant- and animal-derived sources, as well as their subsequent valorization.
For innovation purposes, both modules provide highly efficient tools for qualitative and quantitative analysis, which are of particular importance to companies that orient their production toward export markets. In particular, the pharmaceutical industry can benefit from the analytical capabilities of these modules for compound identification and quantification, advanced drug stability studies, and the detection of degradation products and synthetic impurities.