Lupașcu Lucian

Title/degree Doctor
Position Leading scientific researcher

Organic Syntesis
Ecological Chemistry

Office 312A
Phone/fax (+373 22) 73 99 92
Email [email protected]
[email protected]
[email protected]
Professional links

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Research areas
  • Selection of preparations with the highest inhibitory properties for bacteria and fungi, comparable or more active than the reference antibiotic and antifungal preparations.
  • Study of mechanisms of action of the most effective preparations (establishment of structural changes in microbial cells due to the action of chemicals)
  • Establishing the structure-activity relationship for preparations with antibacterial and antifungal potential (selection of preparations based on the particularities of their chemical structure and activity).
  • Establishment of the effective action time for preparations with high antimicrobial potential (the time during which the preparations manifest their bactericidal or fungicidal properties in its inhibitory concentrations).
Relevant publications


  1. Stingaci, E.; Zveaghinteva, M.; Pogrebnoi, S.; Lupascu, L.; Valica,V.; Uncu, L.; Smetanscaia, A.; Drumea, M.; Petrou, A.; Ciric, A.; Glamoclija, J.; Sokovic, M.;  Kravtsov, V.; Geronikaki, A.; Macaev, F. New vinyl-1,2,4-triazole derivatives as antimicrobial agents: Synthesis, biological evaluation and molecular docking studies. Bioorganic and Medicinal Chemistry Letters. 2020, 30 (17), 127368.
  2. Zinicovscaia I., Ciocarlan A., Lupascu L., Aricu A., Dragalin I., Ciocarlan N. & Yushin N. Chemical analysis of Tanacetum corymbosum (L.) Sch. Bip. using neutron activation analysis. Journal of  Radioanalytical and Nuclear Chemistry, 2019, 321 (3), 349.
  3. Kozakevych R., Bolbukh Y., Lupascu L., Lupascu T., Tertykh V. Polymeric Composite Films with Controlled Release of Natural Antioxidant Enoxil.  Selected Proceedings of the 5th International Conference Nanotechnology and Nanomaterials (NANO2017), August 23-26, 2017, Chernivtsi, Ukraine. In: Nanochemistry, Biotechnology, Nanomaterials, and Their Applications, Springer book 2018, P.149-164,
  4. Ciocarlan A., Dragalin I., Aricu A., Lupascu L., Ciocarlan N., Popescu V. Chemical composition and biological evaluation of Levisticum officinalew.d.j. Koch essential oil. Chemistry Journal of Moldova, 2018, 2(13), 63.
  5. Lupaşcu L., Lupaşcu G., Țîmbaliuc N., Şubina V., Magher M. Activitatea antimicrobiană in vitro a taninurilor intacte şi oxidate, izolate din nuc (juglans regia l.). Buletinul Academiei de Stiințe a Moldovei , 2018, 2, 113. 
  6. Grigorcea S., Lupaşcu L., Țîmbaliuc N., Lupaşcu G. Activitatea antifungică a taninurilor  oxidate, extrase din lemnul de stejar. Intellectus, 2017,3, 94.
  7. Lupașcu  L., Grigorcea  S., Lupașcu  G.,  Țîmbaliuc  N. Noi compuși taninici din stejar și proprietățile lor antimicrobiene in vitro. Buletinul Academiei de Ştiinţe a Moldovei. Ştiinţele vieţii. 2017, 2 (332), 139.
  8. Lupaşcu T., Ţîmbaliuc N., Lupaşcu L. Obţinerea şi caracterizarea compuşilor bioactivi extraşi din produse vegetale forestiere. Akademos, 2017, 4(47), 45.
  9. Lupaşcu L.; Rudic V.; Lupaşcu T.; Gonța A.; Țîmbaliuc N. Oportunităţi de utilizare a taninurilor vegetale intacte şi modificate la tratarea afecţiunilor de origine microbiană. Buletinul Academiei de Ştiinţe a Moldovei. Ştiinţele vieţii. 2016, 2 (329), 125.
  10. Lupașcu L.; Lupașcu T.; Gonța A.; Țîmbaliuc N. Compus autohton de origine taninică cu proprietăți antioxidante. Intellectus, 2016, 3, 94. 


  1. Lupascu L., Volodina G., Rusu M., Cuba L. Water-soluble complexes of Cu(II) with semicarbazone ligands: IR spectroscopy and antimicrobial properties. International Conference “Achievements and perspectives of modern chemistry”, p. 88, Chisinau, octombrie 9-11, 2019
  2. Jovmir T., Lupascu L. Six decades: Review of patent portofolio of the Institute of Chemistry. International Conference “Achievements and perspectives of modern chemistry”, p. 116, Chisinau, octombrie 9-11, 2019
  3. Jovmir T., Popa T., Greta B., Burduniuc O., Lupascu L., Gulea A., Lozan V. Water-soluble complex having antimicrobial activity. International Conference “Achievements and perspectives of modern chemistry”, p. 117, Chisinau, octombrie 9-11, 2019
  4. Lupascu L. Antimicrobial properties of intact and oxidized extracts isolated from commercial green and black tea. International Conference “Achievements and perspectives of modern chemistry”, p. 178, Chisinau, octombrie 9-11, 2019
  5. Timbaliuc N., Lupascu L., Lupascu L. The characterization of the extracts obtained from chestnut seeds. International Conference “Achievements and perspectives of modern chemistry”, p. 196, Chisinau, octombrie 9-11, 2019 
  6. Dragalin I., Lupascu L., Ciocarlan A, Aricu A., Ciocarlan N., Filip F. Chemical composition of essential oil and antimicrobial assessment of extract from Lonicera japonica. International Conference “Achievements and perspectives of modern chemistry”, p. 218, Chisinau, octombrie 9-11, 2019 
  7. Лупашку Л., Цымбалюк Н., Лупашку Г., Слэнинэ В. Антимикробная активность экстрактов танинов из черного чая.  «СВІТОВІ РОСЛИННІ РЕСУРСИ: СТАН ТА ПЕРСПЕКТИВИ РОЗВИТКУ», c. 262-263, June 7, 2019 , V Міжнародної науково-практичної конференції . Матеріали конференції. Kiev,
  8. Lupascu L., Timbaliuc  N., Petrov N., Lupascu T. Antimicrobial activity of extracts from forestry wastes. The 6th International Conference Ecological & Environmental Chemistry-2017, 2-3 march 2017, p. 55.
  9.  Timbaliuc  N., Lupascu T., Petrov N., Lupascu L.  The optimization of the obtaining conditions of the extract from forestry wastes. The 6th International Conference "Ecological & enviromental chemistry"- 2017. March 2-3, 2017, Chisinau, Republic of Moldova, p. 179.
  10.  Lupascu T., Goncear V., Duca Gh., Lupascu L., Timbaliuc N. New compounds for environmental protection and for the human health obtained from the wine secondary products. The 6th International Conference"Ecological & enviromental chemistry"- 2017. March 2-3, 2017, Chisinau, Republic of Moldova, p. 183.
  11. Petrov N., Lupascu T., Timbaliuc N., Lupascu L. Study of the antioxidant properties of the extracts from secondary forest products by chemiluminescence method. The 6th International Conference ECOLOGICAL & ENVIROMENTAL CHEMISTRY- 2017. March 2-3, 2017, Chisinau, Republic of Moldova, p. 222.
  12. Gonta A., Lupascu L., Timbaliuc N., Lupascu T. Investigation of chitosan-based nanocomposits with immobilized natural bactericides. Ukrainian Conference with International participation. 24-25 mai 2017 Kiev, Ukraine, p. 67.
  13. Lupascu T., Timbaliuc N., Lupascu L, Spinu O., Povar I. Research on obtaining enotannins from Moldovan grape seeds. “New trends and strategies in the chemistry of advanced materials with relevance in biological systems, technique and environmental protection”, Timisoara, 10-th edition, 8-9 June, 2017
  14. Lupascu T., Timbaliuc N., Lupascu L., Spinu O., Povar  I. Health significance of the Enoxil preparation. Proceeding of IX-th International Conference in Chemistry. Kyiv-Toulouse, June 4-9, 2017, p.196.
  15. Lupașcu, T.; Lupașcu, L.; Țîmbaliuc, N.; Spînu, O.; Povar, I. Obținerea și aplicarea preparatului Enoxil în agricultură și medicină. Lucrările Conferinței Ştiințifice Internaționale „Perspectivele și Problemele Integrării în Spațiul European  al Cercetării și Educației”, 7 iunie, 2017, Cahul, Republica Moldova, 246-250. ISBN 978-9975-88-019-0 


  1. Turov V., Lupascu T., Bogatyrev V., Krupska T., Galaburda M., Lupașcu L., Povar I., Kokosha N. Material polimeric cu proprietăți antimicrobiene. Patent 4607(MD) din 2017.12.04
  2. Lupaşcu L., Jovmir T., Popa T., Lozan V. Aplicare a 2,6-bis (S-metilizotiosemicarbazidometiliden)-4-metilfenolato-tricloro-dicupru hidrat în calitate de remediu contra bacteriilor fitopatogene. Patent 4663 (MD) din 2019.01.28  

National projects 

  1. ANCD/20.80009.5007.17. Hybrid materials functionalized with carboxyl groups based on plant metabolites with activity against human and agricultural pathogens
    Period: 2020-2023
    Project manager: Dr. habilitate, prof. Fliur MACAEV
  2. CSSDT/15.817.02.16A. Controlling of sorption-structural characteristics of carbonaceous and mineral adsorbents and multifunctional materials for the purpose of their use in practice
    Period: 2015-2019
    Project manager: Acad., dr. habilitate, prof. Tudor LUPAŞCU

International projects

  1. AȘM-ANSIIU/17.80013.5007.02/Ua.  Multicomponent nanocomposites to stimulate the growth of agricultural plants.
    Period: 2017-2018;
    Project manager: Acad., dr. habilitate, prof. Tudor LUPAŞCU
  2. 2020-MSCA-RISE-2016/734641. Nanoporous and Nanostructured Materials for Medical Applications (NANOMED)
    Period: 2017-2020
    Project manager: Acad., dr. habilitate, prof. Tudor LUPAŞCU