Grinco Marina

Title/degree Doctor, assoc. prof.
Position Leading scientific researcher
Laboratory Chemistry of Natural and Biologically Active Compounds
Office 310
Phone/fax (+373 22) 73 97 75
Email [email protected]
Professional links

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IBN
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Research areas

Fine organic synthesis, bioorganic chemistry, chemistry of natural and physiologically active compounds, physico-chemical methods of analysis.

Relevant publications
Projects

Articles in international journals (Web of Science and SCOPUS)

  1. MORARESCU, O., GRINCO, M., KULCIŢKI, V., SHOVA, S., UNGUR, N. An Alternative Approach towards C-12 Functionalized Scalaranic Sesterterpenoids. Synthesis of 17-Oxo-20-norscalaran-12α,19-O-lactone. In: Marine Drugs, 2021, 19(11), 636. DOI: https://doi.org/10.3390/md19110636 (FI 5.118).
  2. МОРАРЕСКУ, О., ГРИНЬКО, М., КУЛЬЧИЦКИЙ, В., БАРБА, А., ГАРБУЗ, О., ГУЛЯ, А. УНГУР, Н. Синтез высокофункционализированных биологически активных тетрациклических дитерпеноидов из энт-каур-16-ен-19-овой кислоты в модифицированных условиях реакции Прево–Вудворда. In: Журнал Органической Химии, 2021, том 57, № 12, с. 1706–1716. (FI 0.959).
  3. MORARESCU, O., GRINCO, M., KULCIŢKI, V., Barba, A., Garbuz, O.; Gulea, A.; Ungur, N. Synthesis of highly functionalized biologically active tetracyclic diterpenoids from ent-kaur-16-en-19-oic acid under modified Prévost-Woodward reaction conditions. In: Russian Journal of Organic Chemistry, 2021, 57, 1931.  DOI: https://doi.org/10.1134/S1070428021120058 (FI 0.723).
  4. MORARESCU, O., GRINCO, M., KULCIŢKI, V., BARBA, A., GARBUZ, O., GUDUMAC, V., GULEA, A., UNGUR, N. A straightforward synthesis of natural oxygenated ent-kaurenoic acid derivatives. In: Synthetic communications, 2020, 50.
    DOI: https://doi.org/10.1080/00397911.2020.1821225 (FI 1.796).

Abstracts

  1. MORARESCU, O., GRINCO, M., KULCIȚKI, V., UNGUR, N. A short and efficient synthesis of a C(12)-functionalized norscalarane. In: The 21st Tetrahedron Symposium - Online, 21 - 24 June 2021. (Reg. number: ETR2021_0497). https://app.oxfordabstracts.com/events/1644/secure/program-app/submission/241851
  2. GRINCO, M., BARBA, A., KULCIŢKI, V. Extraction of pharmaceutical grade lignins and their ozonolytic cleavage in a deep eutectic solvent. In: New frontiers in natural product chemistry. Online scientific seminar, Chisinau, June 4, 2021, Book of Abstracts, p. 28. DOI/IBN: https://doi.org/10.19261/nfnpc.2021.ab21.
  3. GRINCO, M.; BARBA, A.; DUCA, G.; UNGUR, N.; KULCIȚKI, V. The use of qNMR spectroscopy for analytical evaluation of natural extracts. The case of Apple pomace. In: New frontiers in natural product chemistry. Online scientific seminar, Chisinau, June 4, 2021, Book of Abstracts, p. 29. DOI/IBN: https://doi.org/10.19261/nfnpc.2021.ab22.
  4. GÎRBU, V., GRINCO, M., BARBĂ, A., DUCA, GH., UNGUR, N., KULCIȚKI, V. Utilizarea spectroscopiei RMN pentru evaluarea analitică a extractelor de levănțică. Conferinţa Ştiinţifico-practică Națională cu participare Internațională „Actualități și perspective în studiul farmaceutic al plantelor medicinale”. Chișinău, 01 Octombrie 2021. p. 83.

National projects

  1. ANCD/20.80009.8007.03. New products with preventive and therapeutic potential basing on natural products of vegetal origin and modern methods of organic synthesis
    Period: 2020-2023
    Project manager: Dr. habilitat Veaceslav KULCIȚKI 
     
  2. CSSDT/15.817.02.14A. Elaboration of methods for obtaining valuable terpenoids by valorization of renewable resources from Republic of Moldova
    Period: 2015-2019
    Project manager: Dr. habilitate, assoc. prof. Nicon UNGUR
     

International projects:

  1. AȘM-CNCI/15.820.16.02.02/it. Synthesis of guanidine terpenoids with relevant biological activity and therapeutic potential.
    Period: 2015-2016;
    Project manager: Dr. habilitate, assoc. prof. Nicon UNGUR

  2. AȘM-CNCI/18.80013.16.02.02/it. Synthesis of guanidine terpenoids with relevant biological activity and therapeutic potential.
    Period: 2018-2019;
    Project manager: Dr. habilitate, assoc. prof. Nicon UNGUR

  3. SCOPES/IZ73Z0-152346. Modification of natural compounds mediated by free radicals
    Period: 2015-2016
    Project manager: Dr. habilitat Veaceslav KULCIȚKI 

  4. AȘM-STCU/15.820.18.03.07/5984STCU. Unconventional green processes for processing renewable raw materials.
    Period: 2015-2017;
    Project manager: Dr. habilitat Veaceslav KULCIȚKI